A computational platform that used single-cell RNA sequencing (scRNA-seq) data could quickly predict the best chemical compounds to use to convert cells from one type into another for use in research or cell therapies. The work, published in the Nov. 17, 2022, issue of Stem Cell Reports, was a collaboration between the lab of Hongkui Deng, a professor and director of the Key Laboratory of Cell Proliferation and Differentiation at Peking University in Beijing, and the lab of Antonio del Sol, a professor at the Luxembourg Centre for Systems Biomedicine at the University of Luxembourg.

Diwali, the Festival of Light, marks different events depending on where it is celebrated. In some areas of India, it marks the return of Lord Rama to his birthplace of Ayodhya after defeating the demon Ravana.

Researchers at the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne, Australia, have developed a new genome editing technique than can activate any gene, including those that have been silenced, allowing new drug targets and causes of drug resistance to be explored.